Tendências da incidência e da mortalidade do câncer de mama feminino no município de São Paulo / Trends in the female breast cancer incidence and mortality in São Paulo, Brazil

AUTOR(ES)
DATA DE PUBLICAÇÃO

2009

RESUMO

Introduction: Every year, over one million new cases of breast cancer are diagnosed worldwide. Incidence rates are higher in industrialised countries; conversely, mortality rates are higher in developing countries. In Brazil, the highest incidence rates are found in southeastern and southern states. In the last five years, breast cancer incidence rates have increased approximately 30 per cent in most western countries, however, since 2000, a slight decrease has in mortality been observed. Simultaneous investigations on incidence and mortality provide important clues for disease aetiology, and the age-period-cohort model is an useful approach to understand time trends mechanisms. Objectives: To examine time trends in the female breast cancer incidence and breast cancer mortality by age, period and cohort effects. Methods: Incidence was analyzed between 1997 and 2005, and mortality was analyzed between 1982 and 2005. Data were obtained from São Paulo Cancer Registry, Mortality System of Health Ministry, and Brazilian Institute of Geography and Statistic. The effects of age, period and cohort were estimated using a Poisson regression model. Results: Time trends for breast cancer incidence and mortality increase across all age groups, but this effect is more pronounced in mortality rates, especially for women older than 50 years. Period effect in incidence increased between 2003 and 2005, and this coincide with the beginning of the mamography screening programs in São Paulo. The mortality decreased on the same period. The cohort effect in incidence and mortality suggested a decrease in older birth cohort, a levering between 1930 and 1969, and a slight decrease for women born after 1970s. Conclusion: The time trends patterns observed in São Paulo are similar to the ones observed in some developed countries, such United States, Australia and United Kingdom

ASSUNTO(S)

age-periodcohort models. modelos de idade-período-coorte time trends câncer de mama breast cancer incidência mortality incidence tendência mortalidade

ACESSO AO ARTIGO

Documentos Relacionados