Risk factors for laboratory-confirmed bloodstream infection in neonates undergoing surgical procedures
AUTOR(ES)
Romanelli, Roberta Maia de Castro, Anchieta, Lêni Márcia, de Almeida Carvalho, Elaine Alvarenga, da Glória e Silva, Lorena Ferreira, Nunes, Rafael Viana Pessoa, Mourão, Paulo Henrique, Clemente, Wanessa Trindade, Bouzada, Maria Cândida Ferrarez
FONTE
Braz J Infect Dis
DATA DE PUBLICAÇÃO
2014-08
RESUMO
Background Healthcare Associated Infections constitute an important problem in Neonatal Units and invasive devices are frequently involved. However, studies on risk factors of newborns who undergo surgical procedures are scarce. Objective To identify risk factors for laboratory-confirmed bloodstream infection in neonates undergoing surgical procedures. Methods This case–control study was conducted from January 2008 to May 2011, in a referral center. Cases were of 21 newborns who underwent surgery and presented the first episode of laboratory-confirmed bloodstream infection. Control was 42 newborns who underwent surgical procedures without notification of laboratory-confirmed bloodstream infection in the study period. Information was obtained from the database of the Hospital Infection Control Committee Notification of infections and related clinical data of patients that routinely collected by trained professionals and follow the recommendations of Agência Nacional de Vigilância Sanitária and analyzed with Statistical Package for Social Sciences. Results During the study period, 1141 patients were admitted to Neonatal Unit and 582 Healthcare Associated Infections were reported (incidence-density of 25.75 Healthcare Associated Infections/patient-days). In the comparative analysis, a higher proportion of laboratory-confirmed bloodstream infection was observed in preterm infants undergoing surgery (p = 0.03) and use of non-invasive ventilation was a protective factor (p = 0.048). Statistically significant difference was also observed for mechanical ventilation duration (p = 0.004), duration of non-invasive ventilation (p = 0.04), and parenteral nutrition duration (p = 0.003). In multivariate analysis duration of parenteral nutrition remained significantly associated with laboratory-confirmed bloodstream infection (p = 0.041). Conclusions Shortening time on parenteral nutrition whenever possible and preference for non-invasive ventilation in neonates undergoing surgery should be considered in the assistance of these patients, with the goal of reducing Healthcare Associated Infections, especially laboratory-confirmed bloodstream infection.
Documentos Relacionados
- Laboratory-Confirmed Transmission of Vaccinia Virus Infection through Sexual Contact with a Military Vaccinee
- Kinetics of Severe Acute Respiratory Syndrome (SARS) Coronavirus-Specific Antibodies in 271 Laboratory-Confirmed Cases of SARS
- Laboratory-confirmed deaths caused by influenza A (H1N1)pdm09 in the Santa Catarina State, Brazil, 2009-2014
- Bloodstream infection in hematopoietic stem cell transplantation outpatients: risk factors for hospitalization and death
- Risk factors for surgical site infection of pilon fractures