Nonsteroidal anti-inflammatory drug-induced duodenal ulceration and perforation in a mature rottweiler
AUTOR(ES)
Reed, Suma
RESUMO
A mature male rottweiler was evaluated for acute collapse and abdominal pain. The history consisted of concurrent administration of meloxicam and aspirin. On exploratory laparotomy, a large perforated ulcer was discovered in the proximal duodenum, with secondary peritonitis. The pathogenesis of NSAID-induced gastrointestinal ulceration and the supposed safety of COX-2 selective agents are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=339922Documentos Relacionados
- In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System
- In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System
- Drug points: Methotrexate and non-steroidal anti-inflammatory drugs
- Hepatitis induced by non-steroidal anti-inflammatory drugs.
- Nonsteroidal anti-inflammatory drugs and ulcers.
