Monoclonal antibodies to the circumsporozoite protein repeats of a Plasmodium vivax-like human malaria parasite and Plasmodium simiovale.
AUTOR(ES)
Udhayakumar, V
RESUMO
We have recently described a Plasmodium vivax-like human malaria parasite. The circumsporozoite protein of this parasite is identical to that of a simian malaria parasite, P. simiovale, but different from two known types of P. vivax. Here, we describe the production of two monoclonal antibodies, Pam 172 and Pam 135, specific for the circumsporozoite protein repeat sequence APGANQEGGAA of the P. vivax-like malaria parasite. These two monoclonal antibodies recognized air-dried sporozoites of P. simiovale but not other human, simian, or rodent malaria parasites tested.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=186472Documentos Relacionados
- Circumsporozoite protein of the human malaria parasite Plasmodium ovale identified with monoclonal antibodies.
- Metalloprotease Activity in a Small Heat Shock Protein of the Human Malaria Parasite Plasmodium vivax
- Predicted conformations for the immunodominant region of the circumsporozoite protein of the human malaria parasite Plasmodium falciparum.
- A monkey's tale: The origin of Plasmodium vivax as a human malaria parasite
- Antibody response of humans to the circumsporozoite protein of Plasmodium vivax.