Molecular characterization of group A rotavirus before and after the introduction of vaccines in Brazil

AUTOR(ES)

Almeida, Tâmera Nunes Vieira, Fiaccadori, Fabíola Souza, Souza, Menira, Borges, Ana Maria Tavares, Cardoso, Divina das Dôres de Paula

FONTE

Rev. Soc. Bras. Med. Trop.

DATA DE PUBLICAÇÃO

2015-10

RESUMO

ABSTRACTINTRODUCTION:In this study, the molecular characteristics of group A rotavirus (RVA) were compared in samples obtained before and after RVA vaccine-introduction in Brazil.METHODS:Eighty samples were screened for the presence of RVA. Positive samples were molecularly analyzed.RESULTS:RVA positivity was 16.9%, with a predominance of G2P[4]. Periods: pre-vaccination: predominance of IId (G1), IId (G2) lineages, and I1 and E1 genotypes; post-vaccination: predominance of Ib (G1), IIa, and IIc (G2) lineages and I2 and E2 genotypes.CONCLUSIONS:Although changes in RVA-circulation pattern were observed in the post-vaccination period, it could not be attributed to vaccination process.

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