Impacto isolado e associado da terapia hormonal e exercício físico na qualidade de vida em mulheres no climatério pós-menopausa / Isolated and associated effects of hormone therapy and physical exercise on quality of life in climacteric postmenopausal women

AUTOR(ES)

Carolina Kimie Moriyama

DATA DE PUBLICAÇÃO

2007

RESUMO

Objective: The purpose of this study was to evaluate the isolated and associated effects of estrogen therapy (estradiol valerate 1 mg orally/day) and physical exercises (moderate aerobic exercise, 3h/weekly) on quality of life (QOL), health related quality of life (HRQOL) and menopausal symptoms among women who had undergone hysterectomy. Design: It was a six-months, randomized, double-blind, placebocontrolled clinical trial with 44 postmenopausal women who had undergone hysterectomy. The interventions were: physical exercise and hormone therapy (PEHT, n=9); sedentary and hormone therapy (SEDHT, n=14); physical exercise and placebo (PEPLA; n=11), sedentary and placebo (SEDPLA, n= 10). HRQOL was assessed by a Brazilian standard version of SF-36, QOL by WHOQOL-BREF and symptoms by Kupperman Scale, at baseline and after 6 months. Results: There was a decrease of symptoms in all groups, but only groups which performed physical exercises showed increases in QOL and in HRQOL. ANOVA showed that changes in physical functioning (P=0.001), bodily pain (P=0.012), physical domain (P=0,013), psychological domain (P<0,001), and social relationship (P=0,028) scores over the six months period differed significantly between exercisers and sedentaries, regardless of hormone therapy. There were no effects of hormone therapy, and no significant association between physical exercise and hormone therapy in HRQOL. Conclusions: Physical exercises can reduce menopausal symptoms and enhance QOL and HRQOL, independently of taking or not hormone therapy

ASSUNTO(S)

qualidade de vida menopausa menopause quality of life physical exercises hysterectomy histerectomia estrogênios/uso terapêutico exercício estrogen therapy

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