Grandisin caused morphological changes larval and toxicity on Aedes aegypti

AUTOR(ES)

Leite, Ana Carolina C. F., Kato, Massuo J., Soares, Renata O. A., Guimarães, Anthony E., Santos-Mallet, Jacenir R., Cabral, Marise M. O.

FONTE

Revista Brasileira de Farmacognosia

DATA DE PUBLICAÇÃO

24/01/2012

RESUMO

Dengue is a tropical disease caused by an arbovirus transmitted by Aedes aegypti. Since no effective vaccine is available for treating dengue, the present study focused on population vector control through investigating the use of the lignan grandisin, isolated from Piper solmsianum C. DC., Piperaceae, against the larvae of A. aegypti. Grandisin caused larval (L3) mortality at LC50 150 µg/mL. Histological analysis on A. aegypti larvae treated with grandisin (LC50 50 µg/mL) showed changes in the anterior-middle midgut, with intense tissue destruction and cell disorganization.

Documentos Relacionados

• Bioactivity of plant extracts on the larval and pupal stages of Aedes aegypti (Diptera, Culicidea)
• Morphological and morphometrical assessment of spermathecae of Aedes aegypti females
• A comparison of larval, ovitrap and MosquiTRAP surveillance for Aedes (Stegomyia) aegypti
• Effect of phenobarbital on inducing insecticide tolerance and esterase changes in Aedes aegypti (Diptera: Culicidae)
• Efeito da água de criação larval na oviposição de Aedes aegypti em laboratório