Estudo retrospectivo de 3091 casos de neoplasias epiteliais primarias de glandulas salivares maiores e menores intra-orais / Retrospective study of 3091 cases of primary epithelial salivary gland tumors involving the major and minor glands

AUTOR(ES)

Patricia Gemma Strappa Abrahão

DATA DE PUBLICAÇÃO

2009

RESUMO

The aim of this study was to analyse retrospectively the histological and epidemiological characteristics of 3091 cases of intraoral primary epithelial neoplasms of the minor and major salivary glands. It was included on this study, 1766 cases from Brazil, 544 from the U.S., 405 from Uruguay, 151 from Peru, 134 from Guatemala and 91 from Mexico. Benign tumors corresponded to 1757 cases (56.84%), and there were 1334 malignancies ( 43.16%). The main sites of benign and malignant tumours were the parotid gland (n=1291; 41.77%), followed by palate (n= 733, 23.71%) and submandibular gland (n=241, 7.80%). Benign tumours on sublingual gland and intraosseous were not observed. Pleomorphic Adenoma (n=1234, 42.83%) was the predominant benign tumour on major and minor salivary glands, and Mucoepidermoid Carcinoma (n=586, 18.96%) was the most common malignant tumour in all countries but Peru, where the most prevalent malignant tumour was the Adenoid Cystic Carcinoma. Considering all tumors there was a higher prevalence in females (1.31:1), with proportions of 1.46:1 and 1.13:1 for the benign and malignant tumors respectively. Benign tumours had greater incidence on the 5th decade of life and malignancies in the 6th decade. Warthin s tumor and canalicular adenoma had a peak of incidence in the 7th and 8th decades respectively. All 15 intraosseous tumors were malignant, involving mainly the mandible, and mucoepidermoid carcinoma corresponded to 86.67% of the cases. In children and adolescents predominated the benign tumors in all countries studied, and almost all were pleomorphic adenoma. On this age group mucoepidermoid carcinoma was the most prevalent malignant tumor

ASSUNTO(S)

neoplasias bucais mouth neoplasms tumores tumors

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