Avaliação do efeito preventivo do verniz contendo glicerofosfato de cálcio frente a desafios cariogênicos e erosivos / Preventive effect of a varnish containing calcium glycerophosphate after cariogenic and erosive challenges

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

15/04/2011

RESUMO

This study was carried out in four experiments, which aimed at: (1) assess the amount of fluoride (F-) released by the varnishes; (2) assess the amount of loosely and firmly bound F- to dental enamel after the use of varnishes; assess the ability of the varnishes to prevent (3) enamel demineralization from caries and (4) the progression of demineralization from erosion. Fluoride (5,63%) varnishes containing or not calcium glycerophosphate (CaGP) (1%, 5% or 10%) were made and compared to control varnish with no F-, and varnishes containing only F- (either 2.26% or 5.63%). Acrylic plates were used to assess the amount of F- released from the varnishes. A total of 72 human teeth were used to obtain 2 enamel samples per tooth (a and b) to assess the amount of loosely and firmly bound F- to enamel, before (b) and after (a) varnish application. Still, 60 bovine teeth were flattened and treated to assess the preventive effect of the varnishes after in vitro cariogenic challenge. Also, 108 human teeth were treated to assess the effect of the varnishes on the progression of dental erosion in vitro. The varnish containing F (5.63%) and 1% CaGP released more fluoride to the medium (p<0.05), and this same varnish together with the varnish containing F-5.63% promoted a greater quantity of loosely and firmly bound fluoride to dental enamel (p<0.01). However, these aspects were not determinants in the prevention, due to the fact that the varnish containing F (2.26%) showed better preventive effect when it decreased in vitro enamel demineralization from caries (p<0.05) and erosion (p<0.01), but the varnishes containing CaGP did not show the same effect. The use of the varnishes was not able to remineralize enamel which had already suffered softening from an erosive challenge. In view of these results, it may be concluded that, although the varnish containing CaGP with fluoride promoted greater amounts of fluoride released to the medium and greater amounts of loosely and firmly bound fluoride to dental enamel, the CaGP-F varnish did not show a preventive effect after acidic challenges. Therefore, the use of calcium glycerophosphate together with fluoride in varnishes did not show a significant preventive effect for enamel submitted to cariogenic and erosive challenges in vitro.

ASSUNTO(S)

cárie dentária dental caries erosão dentária fluoretos fluoride varnishes fluorides tooth erosion vernizes de fluoretos

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