Antifungals
Mostrando 1-12 de 149 artigos, teses e dissertações.
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1. Synthesis of Hydroxybenzodiazepines with Potential Antioxidant and Antifungal Action
Benzodiazepines derivatives are nitrogen heterocyclic compounds that have various industrial, synthetic, and medicinal applications. Therefore, its potential fully justifies every effort towards the improvement of new, selective, and competent production of these heterocyclic compounds. The novelty of this study encompasses the synthesis of new hydroxylated
J. Braz. Chem. Soc.. Publicado em: 2021-03
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2. Case for diagnosis. Pruritic erythematosquamous lesion in the auricle,
Abstract Chromoblastomycosis is a subcutaneous mycosis with chronic evolution that mainly affects the lower limbs and, less frequently, the auricles. Clinically, it presents with papillary verrucous, nodular, and/or tumoral lesions, whether isolated or infiltrated, forming plaques and, sometimes, atrophic in some areas. Histopathologically, it is characteriz
An. Bras. Dermatol.. Publicado em: 2020-08
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3. New Allyldithiocarbimates: Synthesis, Structure and Antifungal Activity against Phakopsora pachyrhizi and Hemileia vastatrix
Twelve tetraphenylphosphonium allyldithiocarbimates were synthesized and fully characterized by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), infrared and nuclear magnetic resonance (NMR) spectroscopies. The spectroscopic data indicated that the allyldithiocarbimate anions present Z configuration, as confirmed by X-ray crystallograph
J. Braz. Chem. Soc.. Publicado em: 2020-04
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4. Multidrug-resistant Candida glabrata strains obtained by induction of anidulafungin resistance in planktonic and biofilm cells
Candida glabrata has emerged as a common cause of serious life-threatening fungal infections, largely owing to their low susceptibility to azole antifungals. Recent guidance indicates the use of echinocandins as the first-choice drug for the treatment of systemic infections of C. glabrata; however, C. glabrata resistance to echinocandins is reportedly increa
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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5. Antifungal effect of sesame medicinal herb on Candida Species: original study and mini-review
The aim of this study was to evaluate the antifungal susceptibility patterns of three antifungals, methanolic extracts and N-hexane oil of sesame seeds on C. albicans and C. glabrata, isolated from oral cavity of liver transplant recipients. The results were compared with other reports to develop a mini review as well. Candida species were isolated from live
Braz. J. Pharm. Sci.. Publicado em: 23/09/2019
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6. Sensitivity to antifungals by Candida spp samples isolated from cases of chronic atrophic candidiasis (CAC)
Resumo O tratamento de escolha para candidíase atrófica crônica (CAC), também conhecida como estomatite protética, é a terapia antifúngica tópica. Este estudo teve como objetivo isolar, identificar e avaliar a susceptibilidade antifúngica de espécies de Candida de locais mucosos em portadores de prótese com diagnóstico de CAC e determinar a preva
Braz. J. Biol.. Publicado em: 04/07/2019
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7. Yeasts isolated from tropical fruit ice creams: diversity, antifungal susceptibility and adherence to buccal epithelial cells
Resumo Os sorvetes à base de frutas são produtos amplamente consumidos em países tropicais e, devido à sua composição, podem ser uma boa fonte de crescimento microbiano, incluindo patógenos oportunistas. Os objetivos deste estudo foram caracterizar as populações de leveduras presentes nos sorvetes brasileiros à base de frutas e investigar sua susce
Braz. J. Food Technol.. Publicado em: 04/07/2019
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8. Synergistic effect of terbinafine and amphotericin B in killing Fonsecaea nubica in vitro and in vivo
ABSTRACT Chromoblastomycosis is a chronic fungal infection. Itraconazole and terbinafine are the most recommended antifungal drugs for chromoblastomycosis, while amphotericin B is not usually recommended. A patient with chromoblastomycosis in our hospital showed poor clinical responses to itraconazole and terbinafine. The fungus isolated from the lesions o
Rev. Inst. Med. trop. S. Paulo. Publicado em: 19/06/2019
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9. Drug development for cryptococcosis treatment: what can patents tell us?
BACKGROUND Cryptococcosis is one of the most devastating fungal infections in humans. Despite the disease’s clinical importance, current therapy is based on limited antifungals that are either toxic, inefficient, unavailable worldwide, or that quickly lead to resistance. OBJECTIVES The goal of this study was to provide insight into the future of crypto
Mem. Inst. Oswaldo Cruz. Publicado em: 31/01/2019
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10. Antifungal susceptibility of yeasts isolated from anthropogenic watershed
Abstract Yeasts are unicellular fungi widespread in the environment, and studies suggest that there is a positive correlation between yeast and polluted aquatic environments. The aim of this study was to analyze the diversity and resistance of yeasts isolated from water samples collected along the Arroio Dilúvio in Porto Alegre to antifungals. Yeast isolate
An. Acad. Bras. Ciênc.. Publicado em: 17/12/2018
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11. In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
ABSTRACT Griseofulvin (GF) and terbinafine (TF) are commonly used drugs to treat dermatophytosis, a fungal infection of the skin. Today there is an increase in drug resistance to these antifungals which highlight the need for alternative synergistic therapies. Minimum Inhibitory Concentration (MIC) of GF and TF were determined against fungi clinical isolates
Braz. J. Pharm. Sci.. Publicado em: 26/07/2018
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12. Clinical and laboratorial features of oral candidiasis in HIV-positive patients
Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were signif
Rev. Soc. Bras. Med. Trop.. Publicado em: 2018-06