Anemia Sickle Cell
Mostrando 1-12 de 285 artigos, teses e dissertações.
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1. É necessário encaminhar pacientes com traço falciforme ao hematologista?
Não é necessário encaminhar pacientes com traço falciforme ao hematologista.
Portadores de traço falciforme não possuem uma doença, mas uma característica genética que não requer tratamento.
Esse achado é detectado pela eletroforese de hemoglobina ou pelo Teste do Pezinho que identifica mutação de um alelo do gene da hemoglobina,
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. Quais os cuidados devem ser tomados durante o tratamento odontológico de gestantes portadoras de anemia falciforme?
Gestação e anemia falciforme são duas condições especiais das quais o dentista precisa estar ciente para realizar com segurança o atendimento odontológico.
1. Estudos demonstram que o período mais seguro para tratamento em gestantes é durante o segundo trimestre de gestação
. A maioria dos tratamentos odontológicos pode ser reali
Núcleo de Telessaúde Espírito Santo. Publicado em: 12/06/2023
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3. Association Between Lipid Profile and Clinical Manifestations in Sickle Cell Anemia: A Systematic Review
Abstract Introduction Sickle cell anemia (SCA) is a genetic disease associated with frequent episodes of acute illness. Changes in the lipid profile and a chronic inflammatory process make up the molecular aspects observed in this disease. Associations between these mechanisms and clinical manifestations could thus define severity profiles and therapeutic
International Journal of Cardiovascular Sciences. Publicado em: 2022
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4. Follow-up of children with sickle cell anemia screened with transcranial Doppler and enrolled in a primary prevention program of ischemic stroke
ABSTRACT Background: Stroke is a serious complication of sickle cell anemia (SCA). The transcranial Doppler (TCD) is the risk-screening tool for ischemic strokes. The objective of the study was to describe the clinical progression of children with SCA who presented with high risk for stroke by TCD or relevant changes by magnetic resonance angiography (MRA)
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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5. Association between inflammatory molecules, nitric oxide metabolites and leg ulcers in individuals with sickle cell anemia
Abstract Introduction Leg ulcers (LUs) are relatively common in patients with sickle cell anemia (SCA). The role of inflammation and nitric oxide (NO) pathways in the pathophysiology of the LU is not understood. Objective The aim of this study was to verify the association between inflammatory molecules and nitric oxide metabolites (NOx) and the occurrence
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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6. HemoTypeSC point-of-care testing shows high sensitivity with alkaline cellulose acetate hemoglobin electrophoresis for screening hemoglobin SS and SC genotypes
ABSTRACT Introduction: By providing timely actionable results for prompt management, point-of-care testing (POCT) kits have revolutionised medical care for various diseases, ranging from infectious diseases like malaria to genetic disorders, such as sickle cell disease (SCD). They are, however, underutilised in the diagnosis of SCD in developing countries,
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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7. Generation of hematopoietic stem/progenitor cells with sickle cell mutation from induced pluripotent stem cell in serum-free system
ABSTRACT Introduction Sickle cell disease (SCD) is a monogenic disease and it is estimated that 300,000 infants are born annually with it. Most treatments available are only palliative, whereas the allogeneic hematopoietic stem cell transplantation offers the only potential cure for SCD. Objective Generation of human autologous cells, when coupled with ind
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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8. Polymorphisms in the heme oxygenase-1 and bone morphogenetic protein receptor type 1b genes and estimated glomerular filtration rate in Brazilian sickle cell anemia patients
ABSTRACT Introduction Mutations affecting genes involved in oxidative and signaling pathways may be associated with kidney disease in sickle cell anemia. We determined the allele and genotype frequencies of some polymorphisms in the promoter regions of the Heme Oxygenase-1 (HMOX1) [rs2071746 (A > T) and (GT)n repeats, short (S) and long (L) alleles] and Bon
Hematol., Transfus. Cell Ther.. Publicado em: 2021-06
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9. Predictors associated with sickle cell nephropathy: a systematic review
SUMMARY INTRODUCTION: Sickle cell anemia affects more than 30 million people worldwide. Chronic kidney disease develops in 40% of individuals. The death rate of patients with sickle nephropathy is still high, with little known predictors related to its development. To answer the question “What predictors are associated with the onset of chronic kidney dis
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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10. Craniofacial geometric morphometrics in the identification of patients with sickle cell anemia and sickle cell trait
ABSTRACT Objective: The aims of this study were to identify the main characteristics regarding the shape and size of the craniofacial region in patients with sickle cell anemia (SCA) and sickle cell trait (SCT) and in unaffected patients using geometric morphometrics and to check the efficiency of this method. Material and Methods: A cross-sectional analyt
Hematol., Transfus. Cell Ther.. Publicado em: 2020-10
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11. Persistent hematuria among children with sickle cell anemia in steady state
ABSTRACT Introduction: Persistent hematuria is a chronic complication of sickle cell anemia (SCA) which can progress to chronic kidney disease. The practice of early detection of persistent hematuria in children with SCA in steady state is important for timely intervention. Objective: To determine the prevalence of persistent hematuria among children with
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
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12. COVID-19 as a trigger of acute chest syndrome in a pregnant woman with sickle cell anemia
RESUMO: Com grande diversidade genética e distribuição geográfica, Hylaeamys megacephalus (G. Fisher, 1814) ocorre tanto na Amazônia quanto no Cerrado. Visto seu aspecto generalista, esta espécie tolera diversos hábitos alimentares e habitats, ocorrendo em áreas inundadas ou não, sendo predominantemente terrestre, permitindo maior fluxo de genes ent
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09