Analgesic Activity
Mostrando 1-12 de 154 artigos, teses e dissertações.
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1. Effects of erector spinae plane block and retrolaminar block on analgesia for multiple rib fractures: a randomized, double-blinded clinical trial
Abstract Objective: To investigate the effects of Erector Spinae Plane Block (ESPB) and Retrolaminar Block (RLB) on intraand postoperative analgesia in patients with Multiple Rib Fractures (MRFs). Methods: A total of 80 MRFs patients were randomly divided into the ESPB (Group E) and RLB (Group R) groups. After general anesthesia, ESPB and RLB were performed
Brazilian Journal of Anesthesiology. Publicado em: 2022
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2. Analgesic and antiinflammatory activities of the essential oil from Artemisia sieberi Besser
The analgesic activity of Artemisia sieberi oil was assessed by acetic acid-induced writhing test and Eddy’s hot plate method; while the acute anti-inflammatory effect was investigated by inflammatory paw edema test in rats. The administration rout of the essential oil, standard drugs and the vehicle used in all assays was intraperitoneal injection. The 1
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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3. Antinociceptive local activity of 4-allyl-1-hydroxy-2-methoxybenzene (eugenol) by the formalin test: an anti-inflammatory effect
Eugenol has been employed for decades as a condiment, an antimycotic, an antibacterial, an antiviral, and an antioxidant, and it is one of the natural analgesics most frequently utilized for pain and inflammation. Our objective was to determine the analgesic/anti-inflammatory effect of eugenol compared with diclofenac, naproxen, and tramadol using the formal
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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4. Antinociceptive effect of PnTx4(5-5), a peptide from Phoneutria nigriventer spider venom, in rat models and the involvement of glutamatergic system
ABSTRACT Background: The venom of Phoneutria nigriventer spider is a source of numerous bioactive substances, including some toxins active in insects. An example is PnTx4(5-5) that shows a high insecticidal activity and no apparent toxicity to mice, although it inhibited NMDA-evoked currents in rat hippocampal neurons. In this work the analgesic activity o
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 12/08/2019
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5. Fractions of Selaginella convoluta (Arn.) Spring (Selaginellaceae) attenuate the nociceptive behavior events in mice
Resumo Selaginella convoluta é uma espécie popularmente conhecida como “jericó”, e usada na medicina popular como analgésica e anti-inflamatória. Este estudo teve como objetivo investigar em camundongos as atividades antinociceptiva e anti-inflamatória das frações hexânica (Sc-Hex) e clorofórmica (Sc-CHCl3) (100, 200 e 400 mg/kg) obtidas por pa
Braz. J. Biol.. Publicado em: 18/04/2019
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6. Central nervous system and analgesic profiles of Lippia genus
Abstract Many people use medicinal plants to relieve disorders related to the central nervous system, such as depression, epilepsy, anxiety and pain, even though the effectiveness of most of them has not yet been proven through scientific studies. Plants of the Lippia genus, Verbenaceae, are widely used in ethnobotany as a food, for seasoning and in antisept
Rev. bras. farmacogn.. Publicado em: 2019-02
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7. Cryotherapy: biochemical alterations involved in reduction of damage induced by exhaustive exercise
When exercises are done in intense or exhaustive modes, several acute biochemical mechanisms are triggered. The use of cryotherapy as cold-water immersion is largely used to accelerate the process of muscular recovery based on its anti-inflammatory and analgesic properties. The present study aimed to study the biochemical effects of cold-water immersion trea
Braz J Med Biol Res. Publicado em: 04/10/2018
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8. A comparative study of phytoconstituents and antibacterial activity of in vitro derived materials of four Passiflora species
Abstract Passiflora species are well known for their common use in popular medicine for the treatment of several diseases, such as insomnia, anxiety, and hysteria, in addition to their anti-inflammatory, antioxidant, analgesic and antibacterial potential. However, few data about the chemical composition and the medicinal potential of in vitro derived materia
An. Acad. Bras. Ciênc.. Publicado em: 19/07/2018
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9. Essential oils of green cumin and chamomile partially protect against acute acetaminophen hepatotoxicity in rats
ABSTRACT Essential oils of green cumin (Cuminum cyminum) and chamomile (Chamomilla recutita) have antioxidant and anti-inflammatory effects. Acetaminophen, N-acetyl-p-amino-phenol, is an over-the-counter analgesic and antipyretic. Despite being safe at therapeutic doses, acetaminophen overdose is a leading cause of acute liver failure. This study aimed to co
An. Acad. Bras. Ciênc.. Publicado em: 25/06/2018
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10. Bioactive dicaffeoylquinic acid derivatives from the root extract of Calea urticifolia
ABSTRACT Calea urticifolia (Mill.) DC., Asteraceae, is a native plant of the Yucatan Peninsula used in traditional medicine to treat inflammation and pain. The bioassay-guided purification of the ethanol root extract allowed the isolation of the main bioactive metabolites, which were identified as an inseparable mixture of thymol (1) and 3-methyl-4-isopropyl
Rev. bras. farmacogn.. Publicado em: 2018-06
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11. Analgesic effects of Marasmius androsaceus mycelia ethanol extract and possible mechanisms in mice
Marasmius androsaceus is a medicinal fungus mainly used to treat various forms of pain in China. This study investigated the analgesic effects of an ethanol extract of M. androsaceus (MAE) and its potential molecular mechanisms. Oral administration of MAE (50, 200, and 1000 mg/kg) had significant analgesic effects in an acid-induced writhing test, a formalin
Braz J Med Biol Res. Publicado em: 01/03/2018
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12. Antinociceptive activity of Cistanche salsa stolons, growing in the Republic of Kazakhstan
Abstract Herba Cistanche (Cistanche species) in Traditional Chinese Medicine is used for the treatment of several diseases and symptoms, to include pain. The objective of this study was to evaluate the antinociceptive effect of the hydroethanol extract of Cistanche salsa (C.A.Mey.) Beck, Orobanchaceae, stolons in animal models of pain. Chemical composition o
Rev. bras. farmacogn.. Publicado em: 2017-10