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Mostrando 1-12 de 7381 artigos, teses e dissertações.
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1. Fuzzy Boundary for Beams Vibrations in Vehicles
ABSTRACT This work aims to study the transversal motion of a car’s chassis, modeled by a beam and supported at its ends by two sets of spring-damper elements. A finite differences method is utilized along with Robin boundary conditions to solve the mathematical modeling. The constants of the boundary conditions are modeled by a fuzzy parameter obtained thr
Trends in Computational and Applied Mathematics. Publicado em: 2022
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2. Hyperglycemia in hospitalized patients of a tertiary care hospital: prevalence and treatment in two cross-sectional evaluations (2011-2020)
ABSTRACT Objective: A study at Centro Hospitalar Universitário do Porto in 2011 revealed suboptimal control of inpatient hyperglycemia and a similar one was carried out in 2020. This study compares the results of 2011 and 2020 regarding prevalence of hyperglycemia, metabolic control, treatment and glycemic profile by infection/non-infection diagnosis. Sub
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Comparison between somatostatin analog injections
SUMMARY OBJECTIVE: Long-acting depot formulations of somatostatin analogs, i.e., octreotide and lanreotide, are the first-line medical therapies for patients with acromegaly to whom surgery/radiotherapy cannot be performed or who have inadequate response. In this study, we aimed to evaluate the short-term local and systemic adverse reactions developed after
Revista da Associação Médica Brasileira. Publicado em: 2022
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4. Treatment of Hepatitis C with Direct-Acting Antivirals does not Induce Significant Arrhythmias
Abstract Background Chronic Hepatitis C (CHC) therapy with direct-acting antivirals (DAAs) has high efficacy and safety, but some cases of bradyarrhythmias have been described. Objective To evaluate heart rhythm disorders during DAA treatments. Methods Forty-eight patients with CHC (mean 61 years of age; 56% males; 73% HCV genotype 1) were evaluated be
International Journal of Cardiovascular Sciences. Publicado em: 2022
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5. Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi
Furanaphthoquinones are well known in medicinal chemistry for exhibiting relevant structural heterogeneity and bioactivities. In this work, it was synthesized a series of furanaphthoquinones through a tandem reaction between lawsone (8) and cyclic ketones in the presence of morpholine. This strategy provides an efficient and general method for synthesizing f
Journal of the Brazilian Chemical Society. Publicado em: 2022
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6. Finite element computational development for thermo-mechanical analysis of plane steel structures exposed to fire
Abstract This article presents a numerical formulation based on finite element procedures for application in nonlinear thermo-mechanical analyses of steel planar structures under fire condition. The mechanical properties of structural elements degrade when subjected to high temperatures, resulting in significant reductions in strength and stiffness. Under th
REM - International Engineering Journal. Publicado em: 2022
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7. Comparison of the effects of duloxetine and pregabalin on pain and associated factors in patients with knee osteoarthritis
SUMMARY OBJECTIVES: This study aimed to investigate the effects of duloxetine and pregabalin primarily on pain and functional status in patients with knee osteoarthritis and secondarily on quality of life, depression, anxiety, and sleep disturbance. METHODS: A total of 66 patients with knee osteoarthritis were randomized to use duloxetine or pregabalin. Pa
Revista da Associação Médica Brasileira. Publicado em: 2022
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8. Association of FOXO3 polymorphism (rs3800231) and clinical subphenotypes of beta thalassemic individuals
Abstract Introduction Studies have shown that the loss of the FOXO3 transcriptional function is involved in the pathophysiology of some chronic erythroid disorders, including beta-thalassemia (β-thal). Therefore, the single nucleotide polymorphism (SNP) rs3800231 (35-2764A > G) could contribute to alterations in its transcriptional activity, acting as a mo
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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9. Occupational stress and work engagement among primary healthcare physicians: a cross-sectional study
Abstract BACKGROUND: Brazil’s Family Health Strategy is based on a primary healthcare model, which is considered to have case resolution capacity, with physicians at its center. OBJECTIVES: To evaluate the levels of occupational stress and work engagement among primary healthcare physicians. DESIGN AND SETTING: Cross-sectional study conducted in 2017, i
Sao Paulo Medical Journal. Publicado em: 2022
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10. A randomized clinical trial on inhaled ciclesonide for managing acute asthma in the emergency room
ABSTRACT BACKGROUND: Use of inhaled corticosteroids for managing acute asthma exacerbations has been tested since the 1990s. OBJECTIVE: To compare high doses of inhaled ciclesonide with systemic hydrocortisone for managing acute asthma exacerbations in the emergency department. DESIGN AND SETTING: Double-blind, randomized clinical trial in the public heal
Sao Paulo Medical Journal. Publicado em: 2022
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11. Patient's point of view on the diagnosis, treatment, and follow-up in acromegaly: single-center study from a tertiary center
SUMMARY OBJECTIVE: We aimed to evaluate the awareness and perspectives of acromegaly patients in the diagnosis and treatment processes and to evaluate basic clinical and demographic features. METHODS: This cross-sectional study was conducted at the Endocrinology Department of Yildirim Beyazit University between March 2019 and April 2020. A total of 58 acro
Revista da Associação Médica Brasileira. Publicado em: 2022
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12. Epidemiology and risk factors of hypoglycemia in subjects with type 1 diabetes in Brazil: a cross-sectional, multicenter study
ABSTRACT Objective: The aim of this study was to investigate the factors associated with hypoglycemia and severe hypoglycemia (SH) in individuals with type 1 diabetes mellitus (T1D) in Brazil. Materials and methods: This multicenter, cross-sectional study was conducted between August 2011 and August 2014 across 10 Brazilian cities. The data were obtained f
Archives of Endocrinology and Metabolism. Publicado em: 2022