9 Tetrahydrocannabinol
Mostrando 1-12 de 36 artigos, teses e dissertações.
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1. QUANTIFICAÇÃO DE CANABINOIDES EM EXTRATOS MEDICINAIS DE Cannabis POR CROMATOGRAFIA LÍQUIDA DE ALTA EFICIÊNCIA
Cannabidiol (CBD) and tetrahydrocannabinol (THC) are the main active principles in the Cannabis extracts. Rich-CBD extracts are indicated to control seizures in epileptic patients, THC is indicated as antiemetic to patients in chemotherapy treatment and extracts with THC and CBD in proportions of approximately 1:1 are indicated to control spasticity in patie
Quím. Nova. Publicado em: 2020-01
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2. Optimal condition of cannabis maceration to obtain the high cannabidiol and Δ9-tetrahydrocannabinol content
Abstract: The aim of this work was to optimize a maceration condition of cannabis (Cannabis sativa L.). A circumscribed central composite experimental design was applied in this work. Temperature and time were varied from 40-80 °C and 30-90 min, respectively. The three responses (i.e., extraction yield, cannabidiol content, and Δ9- tetrahydrocannabinol con
An. Acad. Bras. Ciênc.. Publicado em: 14/10/2019
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3. Analysis of Isomeric Cannabinoid Standards and Cannabis Products by UPLC-ESI-TWIM-MS: a Comparison with GC-MS and GC × GC-QMS
The Cannabis sativa L. plant has a complex chemical composition, containing various chemical compounds such as terpenes, sugars, hydrocarbons, steroids, flavonoids, and amino acids. Few works have attempted to identify the constitutional isomers of cannabinoids that are found in the plant. The present study reported the analysis of seven cannabinoid standard
J. Braz. Chem. Soc.. Publicado em: 2019-01
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4. A comparative study between two different conventional working electrodes for detection of Δ9-tetrahydrocannabinol using square-wave voltammetry: a new sensitive method for forensic analysis
A maconha é uma das drogas ilícitas mais consumidas no mundo. Sendo assim, os traficantes têm procurado novos meios para mascarar o teste preliminar (colorimétrico) atualmente utilizado. Este trabalho descreve uma metodologia para detecção de delta-9-tetraidrocanabinol (Δ9-THC) por voltametria de onda quadrada (SWV) em meio orgânico N,N-dimetilformam
J. Braz. Chem. Soc.. Publicado em: 2014-03
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5. Effect of (-)-∆9-tetrahydrocannabinoid on the hepatic redox state of mice
(-)-∆9-Tetrahydrocannabinol (∆9-THC), a psychoactive component of marijuana, has been reported to induce oxidative damage in vivo and in vitro. In this study, we administered ∆9-THC to healthy C57BL/6J mice aged 15 weeks in order to determine its effect on hepatic redox state. Mice were divided into 3 groups: ∆9-THC (N = 10), treated with 10 mg/kg bo
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-04
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6. Desenvolvimento e validação de metodologia analítica para a determinação de canabidiol e tetraidrocanabinol em amostras de plasma por cromatografia em fase gasosa/espectrometria de massas / Development and validation of an analytical methodology for determination of cannabidiol and tetrahydrocanabinol in plasma samples using gas phase chromatografy /mass espectrometry
Dissertation (Master). Faculdade de Ciências Farmacêuticas de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, 2008. The Cannabidiol (CBD), that represents about 40% of the cannabinoids found in Cannabis sativa plant, is devoided of the typical psychological and cognitive effects of 9-Tetrahydrocannabinol (9THC). Researches suggest that CBD sho
Publicado em: 2008
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7. Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug
A high dose of delta9-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of delta9-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspec
Brazilian Journal of Medical and Biological Research. Publicado em: 2006-04
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8. Comparative Pharmacology of Δ9-Tetrahydrocannabinol and its Metabolite, 11-OH-Δ9-Tetrahydrocannabinol
A comparison of the psychologic and physiologic effects of intravenously administered Δ9-tetrahydrocannabinol (Δ9-THC) and 11-hydroxy-Δ9-tetrahydrocannabinol (11-OH-Δ9-THC) was carried out in nine casual marihuana smokers. A marked tachycardia and psychologic “high” occurred within 3-5 min after the i.v. administration of 11-OH-Δ9-THC (1 mg) to all
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9. Susceptibility of Naegleria fowleri to delta 9-tetrahydrocannabinol.
Growth of the pathogenic amoeboflagellate Naegleria fowleri is inhibited by delta 9-tetrahydrocannabinol (delta 9-THC). delta 9-THC is amoebostatic at 5 to 50 micrograms/ml. delta 9-THC prevents enflagellation and encystment, but does not impair amoeboid movement. Calf serum at 10 and 20% (vol/vol) reduces the antiamoeba activity of delta 9-THC. Only 1-metho
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10. Nuclear Magnetic Resonance Spectroscopy. 13C Fourier Transform Spectra of Δ8- and Δ9-Tetrahydrocannabinol
Carbon-13 nuclear magnetic resonance spectra have been taken of Δ8- and Δ9-tetrahydrocannabinol. The absorptions have been assigned to specific carbons with the aid of off-resonance and selective proton-decoupling experiments, as well as by chemical-shift comparison with model compounds.
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11. Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro
BioMed Central.
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12. Reintoxication: the release of fat-stored Δ9-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure
Blackwell Publishing Ltd.